Marco Mellado García

INVESTIGADOR CIIMAT

RESUMEN

Profesor de Química de la Universidad de Playa Ancha, Doctorado en Ciencias mención Química y Química Orgánica de la Universidad Federico Santa María.

CONECTAR

INTESTIGACIÓN

.

Profesor de Química de la Universidad de Playa Ancha, Doctorado en Ciencias mención Química y Química Orgánica de la Universidad Federico Santa María.

Próximamente

Design of Hybrid Quinoline–Chalcone Compounds Against Leishmania amazonensis Based on Computational Techniques: 2D- and 3D-QSAR with Experimental …

M Lorca, GC Muscia, J Mella, L Thomaz, JK Yokoyama-Yasunaka, …
Pharmaceuticals 18 (10), 1567
 

Benzo[d]imidazole–Naphthalen-Arylmethanone Regioisomers as CB1 Ligands: Evaluation of Agonism via an Indirect Cytotoxicity-Based Approach

AY Hwa Cho, R Burgos Ravanal, V Zuñiga Salazar, M Mellado, M Lorca, …
International Journal of Molecular Sciences 26 (20), 9986
 
 
 
 

Past and Present of the Antioxidant Studies in Chile: A Bibliometric Study from 2000 to 2024

M Lorca, A Vega-Muñoz, A Acosta, D Cabezas, K Díaz, J Mella, …
Antioxidants 14 (8), 985
 

Synthesis, Biological Activity, and Molecular-Docking Studies of New Brassinosteroid Analogs

M Nuñez, Y Wang, E Russinova, A Estévez-Braun, A Amesty, AF Olea, …
International Journal of Molecular Sciences 25 (18), 10158
 
 
 

Oxidative stress promotes cytotoxicity in human cancer cell lines exposed to Escallonia spp. extracts

C Jara-Gutiérrez, L Mercado, M Paz-Araos, C Howard, M Parraga, …
BMC Complementary Medicine and Therapies 24 (1), 38
 

In silico approaches to develop new phenyl-pyrimidines as glycogen synthase kinase 3 (GSK-3) inhibitors with halogen-bonding capabilities: 3D-QSAR CoMFA/CoMSIA, molecular …

D Cabezas, G Mellado, N Espinoza, JA Gárate, C Morales, …
Journal of Biomolecular Structure and Dynamics 41 (22), 13250-13259
 

Organometallic N‐acylhydrazones of 5‐nitrofuran and 5‐nitrothiophene based: Synthesis, electrochemical, antiparasitic evaluation, and computational study

M Saldías, A Acuña, M Mellado, SR Wilkinson, M Moncada‐Basualto, …
Applied Organometallic Chemistry 37 (12), e7263
 
 

QSAR‐Guided Study for the Microwave‐Assisted Synthesis of 4‐Methylquinoline Derivatives with Antimycobacterial Activity

A Luczywo, M Soto, GC Muscia, GP Romanelli, G Sathicq, C González, …
ChemistrySelect 8 (20), e202300042
 

Synthesis of fluorescent chalcones, photophysical properties, quantitative structure-activity relationship and their biological application

M Mellado, R Sariego-Kluge, F Valdés-Navarro, C González, …
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 291, 122332
 

Cancer and brassinosteroids: Mechanisms of action, SAR and future perspectives

M Lorca, D Cabezas, I Araque, A Terán, S Hernández, M Mellado, …
Steroids 190, 109153
 

Design of benzimidazoles, benzoxazoles, benzothiazoles and thiazolopyridines as leukotriene A4 hydrolase inhibitors through 3D-QSAR, docking and molecular dynamics

M Lorca, M Faundez, DC Pessoa-Mahana, G Recabarren-Gajardo, …
Journal of the Serbian Chemical Society 88 (1), 25-39